Immunization with alpha-toxin toxoid protects the cornea against tissue damage during experimental Staphylococcus aureus keratitis.

نویسندگان

  • E B Hume
  • J J Dajcs
  • J M Moreau
  • R J O'Callaghan
چکیده

Alpha-toxin is a major virulence factor in Staphylococcus aureus keratitis. Active or passive immunization with alpha-toxin toxoid could protect against corneal damage. Results show that either form of immunization did not kill bacteria but did significantly protect against corneal pathology, especially epithelial erosion.

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عنوان ژورنال:
  • Infection and immunity

دوره 68 10  شماره 

صفحات  -

تاریخ انتشار 2000